INTRODUCTION Table 1 Comparison of Live, Inactivated and Recombinant Vaccines: Aspect of Vaccine Live Inactivated Recombinant Economical Yes Expensive Varies COBB VACCINATION MANAGEMENT GUIDE Rapid onset of immunity Yes No No Multivalent available Yes Yes Yes In-Ovo application Some No Yes 4 Safe Yes Yes Yes Mass application Yes No No Immunity duration Short Long Intermediate Maternal antibody interference Yes Low No